金立波，博士，伟德国际1946源于英国生命科学研究院任常务副院长。

曾先后在吉林农业大学科研处、生物反应器与药物开发教育部工程研究中心、生命科学学院、温州市生物医药协同创新中心等多部门任职。2016年8月，入职伟德国际1946源于英国，带领教职工申请并成功获批“浙江省生物医药协同创新中心、生长因子药物开发浙江省工程研究中心”等省级科研平台2项，组建了生物反应器研究与药物开发的研究团队，建立了药学、医学与生物医用材料等多学科相融合的科研模式。

主要科研方向涉及生物医用材料、生长因子基础理论研究、生物药物研究与开发等，近5年内在life sciences、Pharmaceutics、Theranostics、Apoptosis、Materials Science & Engineering C、royal society of chemistry biomaterials-science、Frontiers in Genetics等国内外学术刊物上发表论文30篇(累计IF>90)，其中第一/通讯作者论文20篇(累计IF>60)；申报专利30余项，获授权17项；参与科研项目10项，平台建设项目4项，获吉林省技术发明一等奖1项，长春市科技进步奖1项。

代表性成果：

一、 近年主要期刊论文

（1）Yinai Liu,^#Qianqian Chen,^# Yaoqi Li, Liuliu Bi, Sue Lin, Hao Ji, Da Sun, Libo Jin*, Renyi Peng*.Hydrogen sulfide-induced oxidative stress mediated apoptosis via mitochondria pathway in embryo-larval stages of zebrafish,Ecotoxicology and Environmental Safety,Volume 239,2022,113666,ISSN 0147-6513, (IF:6.291)

（2）Lei Wang，Jiahui Ma，Wei Wu，Yimeng Fang，Fan Liu，Qinsi Yang，Xiang Hu，Xujiang Gu，Zhiying He，Da Sun*，Libo Jin*，Xingxing Zhang*.Effect of aerobic exercise as a treatment on type 2 diabetes mellitus with depression-like behavior zebrafish.life sciences. Volume 300,2022,120578,ISSN 0024-3205,https://doi.org/10.1016/j.lfs.2022.120578. (IF:5.037)，

（3）Yaoqi Li,^#Da Sun,^#Ke Xu*,Libo Jin*,Renyi Peng*. Hydrogen Sulfide Enhances Plant Tolerance to Waterlogging Stress. Plants (Basel). 2021 Sep 16;10(9):1928. doi: 10.3390/plants10091928. PMID: 34579462; PMCID: PMC8468677.(IF:3.935)

（4）Yaoqi Li,^#Qianqian Chen,^# Yinai Liu, Liuliu Bi,Libo Jin*,Ke Xu*,Renyi Peng*.High glucoseinduced ROSaccumulation in embryolarval stages of zebrafish leads to mitochondriamediated apoptosis. Apoptosis, (2022.5.21). https://doi.org/10.1007/s10495-022-01731-2 (IF:4.677)

（5）Haojie Chen,Hao Ji,Xiangjun Kong,Pengyu Lei,Qinsi Yang,Wei Wu,Libo Jin*, Da Sun*. Bacterial Ghosts-Based Vaccine and Drug Delivery Systems. Pharmaceutics 2021.11.8, 13(11), 1892. (IF:6.321)

（6）Nguyen Quoc Viet Hoang, Kong Jie, Naveed Ahmad, Ma Xintong, Zhang Xinyue, Wu Yuhang , Wang Nan, Yao Na, Liu Xiuming, Jin Libo*.Genome-wide identification and expression profiling of flavonoid 3'-hydroxylase gene family in Carthamus tinctorius L.中科院III区，Notulae Botanicae Horti Agrobotanici Cluj-Napoca,2021.11.Volume 49,Issue 4. （12509）(IF:1.444)

（7）Sun Fan,^# Naveed Ahmad,^# Jin Libo,^# Zhang xinyue, Ma Xintong, Nguyen Q. V. HOANG, Ali I. MALLANO, Wang Nan, Yang Zhuoda, Liu Xiuming, Yao Na.Genome-wide investigation of Hydroxycinnamoyl CoA: Shikimate Hydroxycinnamoyl Transferase (HCT) gene family in Carthamus tinctorius L中科院III区，Notulae Botanicae Horti Agrobotanici Cluj-Napoca,2021.09.27.Volume 49,Issue 3. （12489）(IF:1.444)

（8）Libo Jin,^# Guoming Zeng,^# Haojie Chen,Lei Wang,Hao Ji,Sue Lin,Renyi Peng,Da Sun*.Mechanism of lignin degradation via white rot fungi explored using spectral analysis and gas chromatography-mass spectrometry.BioResources. 2021.06.15;Vol16, Issue,5494—5507;(IF:1.614)

（9）Yu-Qing Yan,^#Li-bo Jin,^#Yu Wang,Song-Yan Lu,Yi-Feng Pei,Dong-Wei Zhu,Fu-Sheng Pang,Hao Dong*,Gui-Xue Hu. Goose parvovirus and the protein NS1 induce apoptosis through the AIF-mitochondrial pathway in goose embryo fibroblasts. Research in Veterinary Science, 2021,4.22.vol137,(2021), 68-76(IF：2.534)

（10）Da Sun,Jia Chen,Yuan Wang,Hao Ji,Renyi Peng,Libo Jin*,Wei Wu*.Advances in refunctionalization oferythrocyte-based nanomedicinefor enhancingcancer-targeteddrugdelivery. Theranostics,2019.09.21;Vol. 9, Issue 23，6885—6900；(IF：11.556)

（11）Jing Zhang,Wenhe Zhu,Benkai Xin,Sue Lin,Libo Jin*and Huiyan Wang*. Development of an antibacterial surface with self-defensive and pH-responsive function.royal society of chemistry biomaterials-science, 2019.06.12;2019(9),3795—3800；(IF：5.251)

（12）Libo Jin,Jin Wu,Saverio Bellusci*,Jin-San Zhang*;Fibroblast Growth Factor 10 and Vertebrate Limb Development;Frontiers in Genetics; 2019.01.07，9,(705),1-9；（IF：4.15）

（13）Libo Jin,Jia Chen,Xiaoqing Yan,Chi Zhang,haishan Tian,hao Ji,Lin sue,RenYi Peng,Da sun*.Tripterygium wilfordii polyglycosides inhibit TGF-BETA 1/NF-Kappa B signaling pathway and improve renal fibrosis in diabetic nephropathy．Acta Medica Mediterranea,2019.02.20;(35),2787—2791; （IF：0.835）

（14）Guoming Zeng,^#Libo Jin,^#Qinsi Ying, Haojie Chen,Murinda Charmaine Thembinkosi,ChunguangYang,Jinlong Zhao, Hao Ji,Sue Lin,Renyi Peng,Maolan Zhang,Da Sun;Regulatory T Cells in Cancer Immunotherapy:Basic Research Outcomes and Clinical Directions.Cancer Management and Research,2020:12,10411-10421（IF：2.886）

（15）Libo Jin,Yunpeng Wang,Nuo Xu,Dezhong Wang,Xiuming Liu,Renyi Peng,Chao Jiang,Xiaokun Li*;Expression and activity analysis of β Gallinacin-3 in Arabidopsis.Protein expression and purication,2018.04,(144),1-4; （IF：1.42）

（16）Renyi Peng^#,Hao Ji^#,Libo Jin^#,Sue Lin,Yijiang Huang,Ke Xu,Qinsi Yang,Da Sun*and Wei Wu*;Macrophage-Based Therapies for Atherosclerosis Management.Journal of Immunology Research.2020.01.29,2020,1-11.（IF：3.327）

（17）Da Sun,Jia Chen,Wei Wu,Ju Tang,Li Luo,Kun Zhang ,Libo Jin, Sue Lin,Yitian Gao,Xiaoqing Yan,Chi Zhang. MiR-802 causes nephropathy by suppressing NF-κB-repressing factor in obese mice and human.Journal of Cellular and Molecular Medicine. 2019.02.07,23(4),2863—2871; (IF：4.658)

（18）Sue Lin,Yingjing Miao,Shiwen Su,Jian Xu,Libo Jin,Da Sun,Renyi Peng,Li Huang,Jiashu Cao. Comprehensive analysis of Ogura cytoplasmic male sterility-related genes in turnip (Brassicarapa ssp. rapifera) using RNA sequencing analysis and bioinformatics.Plos One,2019.06.14,14(6),1—29; (IF：2.806)

（19）HaoJi*，KeXu，XiamengDong，DaSun，RenyiPeng，SueLin，KailunZhang，LiboJin；Transcriptional profiling reveals molecular basis and the role of arginine in response to low-pH stress in Pichia kudriavzevii.Journal of Bioscience and Bioengineering.2020.12,130(6),588-595.（IF：2.366）

（20）Sue Lin*,Shiwen Su,Libo Jin,Renyi Peng,Da Sun,Hao Ji,Youjian Yu,Jian Xu*;Identification of microRNAs and their targets in inflorescences of an Ogura-type cytoplasmic male-sterile line and its maintainer fertile line of turnip (Brassica rapa ssp. rapifera) via high-throughput sequencing and degradome analysis.Plos One,2020.7.30,(IF：2.806)

二、 授权发明专利：

1) 一种人源角质细胞生长因子2的基因序列、表达载体及生产方法；201711441853.92

2) 一种肥胖性II型糖尿病斑马鱼模型的构建方法及应用；202110667786.2

3) 一种构建糖尿病型斑马鱼模型的方法；202110297218.8

4) 基于药用植物来源的粉末和药机，2019100396638.9

5) 手术刀清洗装置；201910014373.7；

6) 小型药用植物材料粉碎机，201910065785.3

研究方向：

植物生物反应器。在2006--2015年任职吉林农业大学工程中心副主任9年的时间里，组织中心员工申请获得各级各类研发课题30余项，其中主持国家863计划1项，参与1项，国家自然基金7项，以及教育部、科技厅等部门的科研项目20余项。

获奖情况：

长春市科学技术进步奖 一等奖（市级） 2011.12

吉林省科学技术发明奖 一等奖（省级） 2011.12

教学评建“先进个人” 校级 2007.12

吉林农业大学优秀个人 校级 2004

非典防控工作先进个人 校级 2003

吉林农业大学优秀个人 校级 2000

优秀联络员（连续5年） 长春市国家安全局 1999-2003

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