师资队伍

病毒学研究所

孙文超

来源:伟德国际1946源于英国 日期:2023-01-10浏览量:

个人简介:

孙文超,男,博士,副研究员,硕士生导师,1987年12月生,山东泰安人。

长期致力于动物冠状病毒、小RNA病毒、实验动物病原等新发与再发动物疫病病原感染致病、跨种传播机制,病原拮抗或逃逸宿主天然免疫,病原诱导保护性免疫应答的分子机制研究。在国内外期刊上第一作者/通讯作者发表SCI论文40余篇篇,包括J Virol, Frontiers in Immunology,Transboundary and Emerging Diseases,Marine Pollution Bulletin,Science of Total Environment,GENE,Virus RESEARCH, BMC Veterinary Research等杂志,中文核心期刊30余篇,获得授权发明专利1项,获得吉林省科技进步二等奖1项。主持国家省级等各类项目6项。参与3项国家自然基金、科技部重点研发计划项目等,目前担BMC Veterinary Research,Vaccines、Veterinary Sciences、Animals,Microorganisms等杂志审稿人。

主要研究方向:

动物冠状病毒、小RNA病毒、实验动物病原等新发与再发动物疫病病原感染致病跨种传播机制、病原拮抗或逃逸宿主天然免疫、病原诱导保护性免疫应答的分子机制研究。目前联合培养博士3人。希望对病毒学、免疫学有兴趣的的本科生和研究生加入课题组。

近年发表的部分论文:

[1] Sun W, Du Q, Han Z, et al: Detection and genetic characterization of porcine circovirus 4 (PCV4) in Guangxi, China. Gene 2021, 773:145384.第一作者SCI

[2] Sun W, Wang L, Huang H, et al: Genetic characterization and phylogenetic analysis of porcine deltacoronavirus (PDCoV) in Shandong Province, China. Virus research 2020, 278:197869. 第一作者SCI

[3] Sun W, Wang W, Cao L, et al: Genetic characterization of three porcine circovirus-like viruses in pigs with diarrhoea in China. Transboundary and emerging diseases 2021, 68(2):289-295. 第一作者SCI

[4] Sun W, Wang W, Xin J, et al: An epidemiological investigation of porcine circovirus 3 infection in dogs in the Guangxi Province from 2015 to 2017, China. Virus research 2019, 270:197663. 第一作者SCI

[5] Sun W, Zhang S, Huang H, et al: First identification of a novel parvovirus distantly related to human bufavirus from diarrheal dogs in China. Virus research 2019, 265:127-131. 第一作者SCI

[6] Sun W, Zhang H, Zheng M, et al: The detection of canine circovirus in Guangxi, China. Virus research 2019, 259:85-89. 第一作者SCI

[7] Sun W, Xie C, Liang C, et al: Molecular detection and genomic characterization of Torque teno canis virus in domestic dogs in Guangxi Province, China. Journal of biotechnology 2017, 252:50-54. 第一作者SCI

[8] Wang W#, Sun W#, et al: An epidemiological investigation of porcine circovirus 3 infection in cattle in Shandong province, China. BMC veterinary research 2019, 15(1):60. 共同第一作者 SCI

[9] Liu H#, Li LX#, Sun WC#, et al: Molecular survey of duck circovirus infection in poultry in southern and southwestern China during 2018 and 2019. BMC veterinary research 2020, 16(1):80. 共同第一作者 SCI

[10]. Huang H, Yin Y, Wang W, Cao L, Sun W*, Shi K*: Emergence of Thailand-like strains of porcine deltacoronavirus in Guangxi Province, China. Veterinary medicine and science 2020, 6(4):854-859. 通讯作者 SCI

[11]. Huang H, Li Y, Wang W, Zheng M, Cao L, Sun W*, Lu H: Detection and molecular characterization of novel porcine bufaviruses in Guangxi province. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2020, 82:104286. 通讯作者 SCI

[12] Li Y, Huang H, Lan T, Wang W, Zhang J, Zheng M, Cao L, Sun W*, Lu H: First detection and complete genome analysis of the Lyon IARC polyomavirus in China from samples of diarrheic cats. Virus genes 2021. 通讯作者SCI

[13]Song HC, Yang BT, Zhao T, Sun YF, Zhou JH, Shan XF, Qian AD, Sun WC*, Kang YH: Comparative genomics analysis of strains from diverse sources reveals the evolutionary relationship of Aeromonas veronii. Microbial pathogenesis 2021:105134. 通讯作者SCI

[14] Li Y., Chen S., Shi Y., Huang H., Wang W., Zheng M., Zhao C., Zhang X., Lei X., Sun W*, Liu H., Lan T. Construction and characterization of the full-length cDNA of an infectious clone of emerging porcine teschovirus-2. Pathogens and disease. 2022;80(1). 通讯作者SCI

[15] Liu Y., Lv Q., Li Y., Yu Z., Huang H., Lan T., Wang W., Cao L., Shi Y., Sun W*., Zheng M. Cross-species transmission potential of chicken anemia virus and avian gyrovirus 2. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases. 2022;99:105249. 通讯作者SCI

[16] Yin Y. W., Xiong C., Shi K. C., Xie S. Y., Long F., Li J., Zheng M., Wei X. K., Feng S., Qu S., Lu W., Zhou H., Zhao K., Sun W*., Li Z. Development and application of a multiplex qPCR assay for the detection of duck circovirus, duck Tembusu virus, Muscovy duck reovirus, and new duck reovirus. Virus genes. 2022. 通讯作者SCI

[17]Hai-xin Huang; Chen-chen Zhao; Xiao-xiao Lei; Xin-yu Zhang; Yu-ying Li; Tian Lan; Baopeng Zhao; Jing-yi Lu; Wen-chao Sun; Hui-jun Lu; Ning-yi Jin ; Swine acute diarrhoea syndromecoronavirus (SADS-CoV) Nsp5 antagonizes type I interferon signaling by cleaving DCP1A, Frontiers in Immunology, 2023, 14 通讯作者SCI

[18 ]Haixin Huang; Xiaoxiao Lei; Chenchen Zhao; Yan Qin; Yuying Li; Xinyu Zhang; Chengkai Li;Tian Lan; Baopeng Zhao; Wenchao Sun; Huijun Lu; Ningyi Jin ; Porcine deltacoronavirus nsp5 antagonizes type I interferon signaling by cleaving IFIT3, J Virol, 2024, :e0168223: 1-19 (期刊论文) 共同通讯作者 )

科研课题

[1] 科技部重点研发子课题,猴痘病毒感染转基因小鼠模型建立,10万,2024/1-2027/12,在研,主持。

[2] 浙江省基金-犬圆环病毒ORF2基因PKR信号通路的调控机制(LQ19C180001),10万,2019/01-2021/12,结题,主持。

[3] 温州市项目PDCoV弱毒疫苗的构建及CRISPR/Cas9技术对病毒复制相关宿主分子筛选(N20180010),3万,2018/01-2021/12,结题,主持。

[4] 温州市项目PDCoV NSP3介导的泛素化调节宿主干扰素信号通路的分子机制(N20190005),2万,2019/01-2022/12,结题,主持。

[5] 温州市项目MARCH8-NDP52选择性自噬途径降解猪急性腹泻综合征病毒N蛋白抑制病毒复制的分子机制, 2024/01-2025/12, 4万元, 在研, 主持。

专著、获奖情况及个人荣誉

[1] 2022年获伟德国际1946源于英国优秀教师;

[2] 2022年获吉林省科技进步二等奖,排名第七。

承担的主要课程

病毒与人类健康(本科生课程)

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